
Disease Modifying Anti-Rheumatic Drugs (DMARDs) are the only drugs demonstrated to modify the course of the rheumatoid arthritis and improve radiologic findings. There are 2 types of DMARDs: biologic and syntethic small molecules. Among the biologic DMARDs are tumor necrosis factor alpha (TNF-a) inhibitors; T-cell costimulatory blocking agents and B-cell depleting agents